MYTLab (pronounce as MY-T-Lab = "mighty-lab") is built by principal investigator (PI) Min-Yeh Tsai (MYT), currently an assistant professor at Department of Chemistry, Tamkang University. The MYTLab website is on-line since Dec 1st, 2018.

Research in MYTLab is primarily at the interface of Physical Chemistry and Biology. I employ physicochemical principles to understand biological processes at the molecular level. My research focuses on computational studies on protein-protein/protein-DNA interactions using coarse-grained molecular simulation. The goal of my research aims to understand the significance of functional binding, self-assembly of bio-molecules concerning neurodegenerative diseases as well as related gene transcription regulation.

I will be particularly interested in the research area of computational biophysics and its application in protein aggregation and protein-DNA structure-dynamics-function relationships.

Research Interests

• Termolecular biomolecular physics & chemistry concerning protein-DNA interaction

• Disease-related protein aggregation

• Systems biology of neurodegenerative diseases

Computational Resources

• High performance computing (HPC) PC cluster & workstation

• On-demand cloud resources

• NCHC Taiwania 1

Collaborators

International

• Peter G. Wolynes, Rice University

• Jose N. Onuchic, Rice University

• Margaret S. Cheung, Pacific Northwest National Laboratory;

Local

• Lee-Wei Yang (楊立威), National Tsing Hua University

• Jie-Rong Huang (黃介嶸), National Yang Ming Chiao Tung University